Coming back to pull out loads etc, it’s a long time since I have done strauctural calculations so better to just use a practical approach
The first post and subsequent reply relate to holding the worktop down to the frame and then being able to lift the frame by the worktop.
Holding the top down to the frame really puts no load on teh screw save for resisting a bit of possible cupping
Lifting the frame by the worktop will put more load on the screwed joints. As my photo shows a single 5mm screw will hole 60lbs( anvil, clamp, angle plate) so lets say 25kg per screw. You don’t say what size your frame is but lets assume a 600 x 1200 with one cross member in the middle. Put screws at 200mm cts along the five frame members as that is a total of 21screws.
21 x 25kg = 525kg so even if you could lift that much it is unlikely that the screws will pull out before your arms come out of their sockets.
Now you have said you want to put “heavy” equipment onto the bench. As I have said in this situation the load is all downwards so the screws really only stop the worktop sliding off the frame if you wheel it into soemthing and stop suddenly so no really worries about screw loading there.
Main thin for the last issue is to ensure loads go directly down through worktop, to top frame which sits on the uprights which sit on the casters then all loads are taken by the compression of the materials not by any joints. Most likely failure of a structure like this would be twisting due to lack of triangulation rather than any component failing under compression loads.
As for bolting through the whole thing just watch if there is coolant splashing about as you don’t want moisture getting into the chipboard. Also if counterboring and plugging the holes you will then have your bolt head bearing on the less dense mid layer of the chipboard and not the denser outer layers.
Here is something supported by unistrut, soliid glass basins are 50kg each, ceramic top , metal draw runners and several sheets worth of board, glass fronts and overhang when open. 6 small screws hold it to the horizontal unistrut members and me and my glass guy stood on it to fit the mirrors so downwards loading needs minimal screwing. Though I did not use plugs and screws to hold the unistrut cantilever brackets to the wall behind. All to do with thinking about what loads here are and how they act.