Both my Myford S7 and EW have 8tpi leadscrews, so it is very simply to cut 32 & 40 tpi threads on them – just make sure you use the correct tool form. However, you will probably use ME taps/dies to do this work anyway – unless you need to 'start' the thread for some reason.
For my 'steam' models, I still use BA threads and have all the dies/taps required to do so, as well as a large stock of BA screws/nuts. However, the smaller BA sizes (14/16BA) are now getting very hard to find and where I need something that size or smaller (for my modelling) I've started to use the smaller metric threads.
I also use metric for all my 'new' build tools & fixtures but keep to imperial where the machine was originally built using older screw types. Then, if I go to my 'old' machines, I know what I need in terms of allen key/wrench tools etc e.g. don't mix threads n old machines!
Most (but not all) of my new Chinese stuff uses metric of course.
If I was 30-40 years younger, I would just go with metric but even so, I think ME might be very useful for some things…
Regards,
IanT