They can be used as End Mills, or as small diameter slab mills by cutting on the flutes.
The only thing to take care over is not to exceed a safe depth of cut.
The usual rule of thumb is no more than a quarter of the cutter diameter.
The feed rate should be based on a feed per tooth of about 0.002" (0.050 mm) . The actual feed rate will then be determined by the number of teeth and the rotation speed.
A worn or blunt cutter will need to be treated with more respect and care.
Since the machine will have backlash, it is not advisable to climb mill, for fear of the cutter snatching and pulling itself into the work, to the detriment of both! You might get away with partially locking the travel on that axis, but better to be safe than sorry. Industrial machines will have backlash prevention built in, but not on the machines that we can generally afford!
The work should always approach the cutter so that it is head on to the approaching cutter teeth.
Overdo things and you might be in market for a new cutter!
HTH
Howard