I have often pondered this question. It seems to me if you need replace eccentrics, though they should have a long life, removing and re-fitting press-fitted wheels to do so is not best practice.
Looking at the facsimile above, I can see one possible trap though.
If the bore and the split are not spot-on to very fine limits, tightening the screw to close its side could open the other, maybe by only a “thou” but possibly enough to cause problems.
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Split eccentrics were common in full-size practice, but not as that ME article.
Instead, referring to the diagram, two screws, actually studs and nuts were used, in the wide parts at right-angles to the single screw shown. There is less metal there so making them reliably, in small scales, won’t be easy; but it would give equal clamping.
To accommodate them the nuts were housed in apertures through the half-sheave, rather than radial holes from the rim; but that may be troublesome on anything smaller than 7.25″ gauge, and not exactly easy there. You’d hit access problems for the spanner with two eccentrics side-by-side in a narrow space.
[I’ve an idea it is no less than S.M.E.E. whose club badge is based on one such eccentric, with its distinctive “windows” .]
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The large engines’ eccentrics are keyed to the crankshaft, needing correct locations to start with, determined by careful drawing and calculations. I think some workshops used templates to set the key-way cutting.
Given that in principle, Stephenson’s Link Motion is all symmetrical about the crank at dead-centres, especially with a centrally-suspended expansion-link, I am not sure why angular adjustment should be needed, other than on locomotives whose piston-rods and valve-spindles are not radial to the axle. Axial adjustment on the valve-spindle is still necessary, to deal with slight tolerance accumulations.
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Regarding the eccentric described, it uses the conventional channelled rim to retain the strap sideways. For my engine I opted instead to turn plain surfaces but cut a thin groove in both the cast-iron sheave and mild-steel strap, at mid-thickness, to take a split mild-steel ring like a circlip. Indeed, a commercial circlip with the ends trimmed off might be used. It is fitted to the sheave in a manner similarly to installing a piston-ring.