It is surprising how flexible a standard set of gears can be, if you seek 'unusual' pitches. I'll try to explain without any advanced maths.
Imagine a simple gear train that includes a 55 too drive and 60 tooth driven gear. Calculated pitch is slightly too great, and you need to reduce it. the reduction is 55/60 or 1:0.917
If you only have wheels with multiples of five teeth, you can change to a 60 driver and 65 driven. Giving 60/65 or 0.923. That's roughly a 1% change. give or take, if you have plenty of wheels in 5-tooth steps you can cover a range in roughly 1-2% steps (bigger steps with smaller wheels).
Regardless of the metric/imperial conversion this is where 63 (and the unbiquitous 57) come in handy. By splitting the 55-60 and 60-65 steps they allow you a whole series of smaller adjustments of nearer 0.5%.
In fact for gears around mid range and using a two step train (which allows two odd gears to be used if required) it becomes possible to get around 0.2% accuracy for many 'odd' threads. This is fine for fixings, and some basic measurement/leadscrew purposes.
Whether you use trial and error or some number crunching programme to find you ratios is irrelevant, you should still be able to get reasonable results with a set of 5-step gears a couple of "od un's".
Neil