Ideally, a taper pin will be an exact fit in the taper hole.
We all know how much force is required to break a morse taper, and they have an angle of 2 -3 degrees
On many of the full size locos that I have ssen the nut is locked by a taper pin hammered through the nut and pin.
In my experience, a taper pin, well hammered home, will take a lot to remove it.
A properly fitted split pin is a very effective way of preventing nuts coming loose.
Personally, I do like wire locking, but time consuming to do, and is reaslly intended to prevent threadeds fasteners fron unscrewing. Very popular in aircraft practice (Excepting Boeing doors!)
Howard