I was recently working with a product designer using M6 bolts into 3D printed parts. Thinking that the strongest result would be to have a metal – metal thread, Helicoils were being inserted into the plastic parts. Unfortunately, they appeared to self-tap into the holes without needing to used the supplied tap to cut a thread first.
The result was that on inserting the M6 bolt, the coil tried to extend to its design pitch which internally de-laminated the printed part, seriously (though not terminally) weakening it. Not visible from the surface, but recognisable by the creaking sound of the material splitting internally.
Although this was the result of incorrect process, I imagine that simply self-tapping a machine screw could have similar results, especially if the metal thread pitch 'beats' with the layer thickness.
David
(long-time lurker from Nottingham)