Well how long is a bit of string? or how much money have you got?. Ballscrews generally have less backlash and can wear at a lower rate but it depends on their construction i.e. cost. Cheaper rolled screws are formed by rollers under extreme presssure, More expensive screws are ground and more accurate. If you don’t keep the junk out of the nut it can wear although they don’t seem to jam. The manufacturer can then fit different size balls to tighten it back up if local screw wear has not happened.
The Acme thread is a lot less efficient -harder to turn – but the nut should be adjustable to remove the backlash. Real issue is that after some time the screw wears in the most used parts then you can’t have uniform nut tightness along the whole thread. A CNC machine tends to have a lot more action on the leadscrews than a manual machine so some sort of pressurised central lubrication system is very desirable -even essential with acme screws.
Many commercial machines use belts to connect the screw to motor, the belts are not a problem, with home use you may not need to ever change the belt. Some designers use the belt drive to change the torque/ speed/ step size or to tuck the motor underneath.
Oldhams can wear, the bellows coupler can be better long term. The coupler tends to be longer than the belt solution so the motor sticks out more. Some use rigid or no couplers, nipping the stepper flange bolts up last and praying that the screw and motor end up on the same axis.
Software can compensate the average backlash, a good test is a nest of circles stepped by 0.1″ in alternate cutting directions or a square at 45 degrees to the X axis.
So how much backlash ? Well the stiffness of the machine is another big limiting factor. Given perfect ways and gibbs with great screws, if the machine is bendy then climb milling may end up badly.
You could fit the drives to the existing screws and add one shot oiling and linish the gibs then see how it runs. If or when screw wear is an issue then you can always fit ballscrews.
Regards,
Alan.