The biggest enemy of cutters on milling machines, manual or CNC is recirculating the already cut chips.
If you think about it it makes a lot of sense when you realise that a lump of chip getting stuck into the leading edge of a cutter will deflect the cutter off it part before it either gets recut or wedges itself past the tooth.
So the trick is to keep the cut clear, coolant works but for it to work effectively you needs loads of it, not a drip or a dribble, all that does is cools the job down a bit and provides a bit of lubrication but the chips are still there.
You need enough to completely was the job clean. However unless you have shrouded machines like in industry you are on a looser as regards mess.
Air blast does the same job and is not quite as messy, you don't need to work in a wet suit but it still throws chips all over.
You have to address guarding / screens as much as chip removal.
The smaller the cutter the more problem recutting chips is, you only need a slight deflection on a small cutter for it to snap.