Hi Steve,
It sounds a bit odd that you should be knackering plugs after a few minutes running and it does point towards a coil break-down as Patrick said when the coil warms up. Have you actually tested the continuity through the plugs to check that they are indeed dead?
Have you re-tried any of your “dead” plugs after a cooling down period?
Another thing you could try when the fault occurs next, is to remove the spark plug wire from the end of the plug and (using a pair of insulated pliers!) hold the end of the plug wire just off any bare metal surface on your engine and flick over the flywheel and see if you get a spark from the end of the wire. If you get a spark then probably the plug is faulty. If you get no spark then you need to look elsewhere, coil, points, condenser & also check all the associated connections are clean and tight. One thing quite often overlooked is the plug lead itself. Check the continuity through the plug lead. Quite often a broken plug lead will allow a spark to jump the gap in open air when carrying out the test above but will fail to give an adequate spark for ignition in the pressurised confines of the combustion chamber.
Hope these few pointers may help but ,as Andy requested above, a few more details of what happens and what you’ve actually tried would be good!
Regards, Martin.